A meta-analysis of frequency studies found that training a muscle group twice per week produced greater hypertrophy than once per week. When total weekly volume is equated, however, the added benefit of frequency largely reflects the ability to accumulate more quality volume rather than frequency itself.
- Schoenfeld BJ, Ogborn D, Krieger JW (2016). Effects of Resistance Training Frequency on Measures of Muscle Hypertrophy: A Systematic Review and Meta-Analysis doi:10.1007/s40279-016-0543-8